Peripheral T-Cell Lymphomas of the T Follicular Helper Type: Clinical, Pathological, and Genetic Attributes
نویسندگان
چکیده
Follicular helper T-cell (TFH) lymphomas comprise a unique group of that represent neoplastic proliferations follicular T-cells and share genetic, immunophenotypic, morphologic, clinical features. Angioimmunoblastic lymphoma (AITL) is the prototypical TFH lymphoma; in addition, 2017 revised World Health Organization (WHO) 4th edition recognizes two other subtypes: (FTCL) nodal peripheral with T phenotype (PTCL-TFH). This review discusses morphologic spectrum, immunophenotype, diagnostic mimics/pitfalls, genetic attributes this category lymphomas.
منابع مشابه
Peripheral T-cell lymphomas with a follicular growth pattern are derived from follicular helper T cells (TFH) and may show overlapping features with angioimmunoblastic T-cell lymphomas.
Rare cases of peripheral T-cell lymphomas with follicular growth pattern (PTCL-F) have been recently reported, and their association with t(5;9)(q33;q22) involving ITK and SYK has been suggested. However, the clinicopathologic aspects of PTCL-F are poorly described and the normal cell counterpart of this subgroup of lymphoma is still unknown. Therefore, we analyzed the pathologic, phenotypic, a...
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ژورنال
عنوان ژورنال: Hemato
سال: 2022
ISSN: ['2673-6357']
DOI: https://doi.org/10.3390/hemato3010020